HIF-1α pathway
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HIF-1α pathway: role, regulation and intervention for cancer therapy2015年6月6日 · Activation of HIF-1 transcription factor is the most recognized pathway adopted by hypoxic cells in this harsh microenvironment (reviewed in ... tw | twHypoxia-Inducible Factor (HIF)-1 Regulatory Pathway and its ... - NCBIThis review focuses on the potential of the HIF-1 pathway in therapeutic intervention for the treatment of diseases such as cancer and ischemia. tw | tw圖片全部顯示Brusatol inhibits HIF-1 signaling pathway and suppresses glucose ...2016年12月16日 · Hypoxia-inducible factor-1 (HIF-1) is an important transcription factor that induces adaptive responses upon low oxygen conditions in human ...ASC modulates HIF-1α stability and induces cell mobility in OSCC2020年9月3日 · Molecules involved in the HIF-1α pathway, such as VHL and PHD2, ... It is an aggressive cancer that leads to death; in Taiwan, ...Hypoxia-inducible factor pathway and diseases of the vascular wallIncreased HIF-1α may contribute to atherosclerosis through alteration of smooth muscle cell proliferation and migration, angiogenesis, and lipid metabolism. The ... tw | twOverexpression of hypoxia-inducible factor and metabolic pathways2017年11月13日 · An extensive study on the regulation of each step of these pathways may help find a potential cancer target. Up-regulated HIF-1 expression and ... tw | twPI3K/Akt and HIF‑1 signaling pathway in hypoxia‑ischemia (Review)2018年8月9日 · HIF-1α is regulated by PI3K/Akt signaling pathway ... Semenza GL: Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and ...Imaging of the hypoxia-inducible factor pathway: insights into ...The transcription factor complex hypoxia-inducible factor (HIF)-1 controls the expression of most genes involved in adaptation to hypoxic conditions. HIF-1 is a ... tw | twNon-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 ...2017年11月27日 · Hypoxia-inducible factor 1 alpha (HIF-1α) orchestrates cellular ... axis is the major pathway involved in promoting HIF1A transcription and ...