Punicalagin - Immunology & Inflammation - Selleck Chemicals
文章推薦指數: 80 %
Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects. Selleckchem.com Close ChooseYourCountryorRegion UnitedStates Germany China Japan UnitedKingdom France Korea Netherlands Canada Italy Australia Austria Belgium Canada China CzechRepublic Denmark Finland France Germany Greece HongKong Hungary Iceland India Ireland Israel Italy Japan Korea Luxembourg Malaysia Netherlands NewZealand Norway Poland Romania SaudiArabia Singapore Spain Sweden Switzerland Taiwan Turkey UnitedKingdom UnitedStates OtherCountries COVID-19 BioactiveCompounds BySignalingPathways PI3K/Akt/mTOR Epigenetics Methylation Immunology&Inflammation ProteinTyrosineKinase Angiogenesis Apoptosis Autophagy ERstress&UPR JAK/STAT MAPK CytoskeletalSignaling CellCycle TGF-beta/Smad DNADamage/DNARepair StemCells&Wnt Hippo Ubiquitin NeuronalSignaling NF-κB GPCR&GProtein Endocrinology&Hormones TransmembraneTransporters Metabolism Proteases Microbiology Others Byproducttype NewProducts InVivoAntibodies TherapeuticAntibodies PfizerLicensedProducts ActivePharmaceuticalIngredients NaturalProducts ModelCompounds Peptides Antibiotics Antibody-drugConjugates(ADC) PROTAC HydrotropicAgents Dyes ·AllTargets(A-Z) ·AllProducts(A-Z) CompoundLibraries PopularCompoundLibraries CustomizeLibrary ClinicalandFDA-approvedRelated BioactiveCompoundLibraries InhibitorRelated NaturalProductRelated MetabolismRelated CellDeathRelated BySignalingPathway ByDisease Anti-infectionandAntiviralRelated NeuronalandImmunologyRelated FragmentandCovalentRelated FDA-approvedDrugLibrary FDA-approved&PassedPhaseIDrugLibrary Preclinical/ClinicalCompoundLibrary BioactiveCompoundLibrary-I BioactiveCompoundLibrary-Ⅱ KinaseInhibitorLibrary Express-PickLibrary NaturalProductLibrary HumanEndogenousMetaboliteCompoundLibrary AlkaloidCompoundLibraryNew AngiogenesisRelatedcompoundLibrary Anti-AgingCompoundLibrary Anti-alzheimerDiseaseCompoundLibrary AntibioticscompoundLibrary Anti-cancerCompoundLibrary Anti-cancerCompoundLibrary-Ⅱ Anti-cancerMetabolismCompoundLibrary Anti-CardiovascularDiseaseCompoundLibrary Anti-diabeticCompoundLibrary Anti-infectionCompoundLibrary AntioxidantCompoundLibrary Anti-parasiticCompoundLibrary AntiviralCompoundLibrary ApoptosisCompoundLibrary AutophagyCompoundLibrary CalciumChannelBlockerLibraryNew CambridgeCancerCompoundLibrary CarbohydrateMetabolismCompoundLibraryNew CellCyclecompoundlibrary CNS-PenetrantCompoundLibrary CovalentInhibitorLibrary CytokineInhibitorLibraryNew CytoskeletalSignalingPathwayCompoundLibrary DNADamage/DNARepaircompoundLibrary Drug-likeCompoundLibrary EndoplasmicReticulumStressCompoundLibrary EpigeneticsCompoundLibrary ExosomeSecretionRelatedCompoundLibraryNew FDA-approvedAnticancerDrugLibraryNew FerroptosisCompoundLibrary FlavonoidCompoundLibrary FragmentLibrary GlutamineMetabolismCompoundLibrary GlycolysisCompoundLibrary GPCRCompoundLibrary GutMicrobialMetaboliteLibrary HIF-1SignalingPathwayCompoundLibrary HighlySelectiveInhibitorLibrary Histonemodificationcompoundlibrary HTSLibraryforDrugDiscovery HumanHormoneRelatedCompoundLibraryNew HumanTranscriptionFactorCompoundLibraryNew Immunology/InflammationCompoundLibrary InhibitorLibrary IonChannelLigandLibrary JAK/STATcompoundlibrary LipidMetabolismCompoundLibraryNew MacrocyclicCompoundLibrary MAPKInhibitorLibrary MedicineFoodHomologyCompoundLibrary MetabolismCompoundLibrary MethylationCompoundLibrary MouseMetaboliteCompoundLibraryNew NaturalOrganicCompoundLibrary NeuronalSignalingCompoundLibrary NF-κBSignalingCompoundLibrary NucleosideAnalogueLibrary ObesityCompoundLibrary OxidativeStressCompoundLibraryNew PhenotypicScreeningLibrary PI3K/AktInhibitorLibrary ProteaseInhibitorLibrary Protein-proteinInteractionInhibitorLibrary PyroptosisCompoundLibrary SmallMoleculeImmuno-OncologyCompoundLibrary StemCellDifferentiationCompoundLibraryNew StemCellSignalingCompoundLibrary TGF-beta/Smadcompoundlibrary TraditionalChineseMedicineLibrary TyrosineKinaseInhibitorLibrary UbiquitinationCompoundLibrary CherryPicking YoucanpersonalizeyourlibrarywithchemicalsfromwithinSelleck'sinventory.Buildtherightlibraryforyourresearchendeavorsbychoosingfromcompoundsinallofouravailablelibraries. [email protected]. Youcouldselect: SpecificCompounds Quantities 96or384wellPlateMap Dry/solidorDMSOsolution Antibodies InVivoAntibodies TherapeuticAntibodies Bioreagents qPCR 2xSYBRGreenqPCRMasterMix 2xSYBRGreenqPCRMasterMix(LowROX) 2xSYBRGreenqPCRMasterMix(HighROX) ProteinAssay ProteinA/GMagneticBeadsforIP Anti-Flagmagneticbeads Anti-FlagAffinityGel Anti-Mycmagneticbeads Anti-HAmagneticbeads MagneticSeparator PolyFLAGPeptidelyophilizedpowder ProteaseInhibitorCocktail ProteaseInhibitorCocktail(EDTA-Free,100XinDMSO) PhosphataseInhibitorCocktail(2Tubes,100X) CellBiology CellCountingKit-8(CCK-8) AnimalExperiment MouseDirectPCRKit(ForGenotyping) NewProducts ContactUs Headquarters WorldwideDistributors Home Immunology&Inflammation Immunology&Inflammationrelatedchemical - Anti-infectionchemical Punicalagin Punicalagin CatalogNo.S9131 Forresearchuseonly. Punicalagin,amajorellagitanninfoundinpomegranateextracts,hasbeenshowntohaveantioxidant,anti-inflammatory,andanticancereffects. CASNo.65995-63-3 Selleck'sPunicalaginhasbeencitedby1Publication Purity&QualityControl ChooseSelectiveImmunology&InflammationrelatedInhibitors RelatedCompoundLibraries KinaseInhibitorLibrary FDA-approvedDrugLibrary NaturalProductLibrary BioactiveCompoundLibrary-I BioactiveCompoundLibrary-Ⅱ HighlySelectiveInhibitorLibrary Express-PickLibrary BiologicalActivity Description Punicalagin,amajorellagitanninfoundinpomegranateextracts,hasbeenshowntohaveantioxidant,anti-inflammatory,andanticancereffects. Protocol(fromreference) Solubility(25°C) Invitro ChemicalInformation MolecularWeight 1084.72 Formula C48H28O30 CASNo. 65995-63-3 Storage 3years -20°C powder 2years -80°C insolvent Smiles C1C2C(C3C(C(O2)O)OC(=O)C4=CC(=C(C(=C4C5=C(C(=C(C=C5C(=O)O3)O)O)O)O)O)O)OC(=O)C6=CC(=C(C(=C6C7=C(C(=C8C9=C7C(=O)OC2=C(C(=C(C3=C(C(=C(C=C3C(=O)O1)O)O)O)C(=C92)C(=O)O8)O)O)O)O)O)O)O InvivoFormulationCalculator(Clearsolution) Step1:Enterinformationbelow(Recommended:Anadditionalanimalmakinganallowanceforlossduringtheexperiment) Dosage: mg/kg Averageweightofanimals: g Dosingvolumeperanimal:μL Numberofanimals: Step2:Entertheinvivoformulation(Thisisonlythecalculator,notformulation.PleasecontactusfirstifthereisnoinvivoformulationatthesolubilitySection.) %DMSO + % PEG300 Cornoil + %Tween80 + %ddH2O %DMSO+ % Cornoil PEG300 CalculateReset Calculationresults: Workingconcentration:mg/ml; MethodforpreparingDMSOmasterliquid:mgdrugpre-dissolvedinμLDMSO(Masterliquidconcentrationmg/mL,PleasecontactusfirstiftheconcentrationexceedstheDMSOsolubilityofthebatchofdrug.) Methodforpreparinginvivoformulation:TakeμLDMSOmasterliquid,nextaddμLPEG300,mixandclarify,nextaddμLTween80,mixandclarify,nextaddμLddH2O,mixandclarify. Methodforpreparinginvivoformulation:TakeμLDMSOmasterliquid,nextaddμLCornoil,mixandclarify. Note:1.Pleasemakesuretheliquidisclearbeforeaddingthenextsolvent. 2.Besuretoaddthesolvent(s)inorder.Youmustensurethatthesolutionobtained,inthepreviousaddition,isaclearsolutionbeforeproceedingtoaddthenextsolvent.Physicalmethodssuch asvortex,ultrasoundorhotwaterbathcanbeusedtoaiddissolving. MolarityCalculator Mass Concentration Volume MolecularWeight pg ng μg mg g kg = fM pM nM μM mM M × nL μL mL L × Calculate Reset DilutionCalculator MolecularWeightCalculator TechSupport Answerstoquestionsyoumayhavecanbefoundintheinhibitorhandlinginstructions.Topicsincludehowtopreparestocksolutions,howtostoreinhibitors,andissuesthatneedspecialattentionforcell-basedassaysandanimalexperiments. HandlingInstructions Tel:+1-832-582-8158Ext:3 Ifyouhaveanyotherenquiries,pleaseleaveamessage. *IndicatesaRequiredField *Name Pleaseenteryourname. *Email Pleaseenteryouremail. Pleaseenteravalidemailaddress. Phone *Comments: Pleasewritesomethingtous. Tags:buyPunicalagin|Punicalaginsupplier|purchasePunicalagin|Punicalagincost|Punicalaginmanufacturer|orderPunicalagin|Punicalagindistributor Selleck AboutUs Careers SiteMap ProductCatalogs TechSupport PharmacologicalGlossary Abbreviations QualityManual InquiryForm(TechSupport) MolarityCalculator DilutionCalculator MolecularWeightCalculator InvivoFormulationCalculator(Clearsolution) Service HowtoOrder Terms&Conditions VendorRegistrationID CreditCardPayment SafeShopping PrivacyPolicy GetaW-9Form ReturnisEasy UnconditionalReturn&ReplacementPolicy FreeOvernightDelivery OnAllOrdersover$500 Tel:+1-832-582-8158Fax:+1-832-582-8590 Email:[email protected] Tel:+498996057095 Email:[email protected] SeeWorldwideDistributors Productsareforresearchuseonly.Notforhumanuse.Wedonotselltopatients. ©Copyright2013SelleckChemicals.AllRightsReserved. × CellLines AssayType Concentration IncubationTime Formulation ActivityDescription PMID × (clickthelinktoreviewthepublication) × DilutionCalculator Calculatethedilutionrequiredtoprepareastocksolution.TheSelleckdilutioncalculatorisbasedonthefollowingequation: Concentration(start)xVolume(start)=Concentration(final)xVolume(final) Thisequationiscommonlyabbreviatedas:C1V1=C2V2(InputOutput) C1 V1 C2 V2 fM pM nM μM mM M × nL μL mL L = fM pM nM μM mM M × μL mL L Calculate Reset *Whenpreparingstocksolutionsalwaysusethebatch-specificmolecularweightoftheproductfoundontheviallabelandMSDS/COA(availableonline). TheSerialDilutionCalculatorEquation SerialDilutions Concertration(start): Dilution-folds: Calculate ComputedResult C1=C0/X C1: LOG(C1): C2=C1/X C2: LOG(C2): C3=C2/X C3: LOG(C3): C4=C3/X C4: LOG(C4): C5=C4/X C5: LOG(C5): C6=C5/X C6: LOG(C6): C7=C6/X C7: LOG(C7): C8=C7/X C8: LOG(C8): × MolecularWeightCalculator Enterthechemicalformulaofacompoundtocalculateitsmolarmassandelementalcomposition: Calculate TotalMolecularWeight:g/mol Tip:Chemicalformulaiscasesensitive.C10H16N2O2c10h16n2o2 Instructionstocalculatemolarmass(molecularweight)ofachemicalcompound: Tocalculatemolarmassofachemicalcompound,pleaseenteritschemicalformulaandclick'Calculate'. Definitionsofmolecularmass,molecularweight,molarmassandmolarweight: Molecularmass(molecularweight)isthemassofonemoleculeofasubstanceandisexpressedintheunifiedatomicmassunits(u).(1uisequalto1/12themassofoneatomofcarbon-12)Molarmass(molarweight)isthemassofonemoleofasubstanceandisexpresseding/mol. × Immunology&InflammationrelatedSignalingPathwayMap
延伸文章資訊
- 1Punicalagin = 98 HPLC, pomegranate 65995-63-3
Punicalagin is one of the main ellagitannins (ETs) or hydrolyzable tannins present in pomegranate...
- 2Punicalagin and Ellagic Acid Demonstrate Antimutagenic ...
Punicalagin (PC) is an ellagitannin found in the fruit peel of Punica granatum. We have demonstra...
- 3Punicalagin, a polyphenol in pomegranate juice ... - NCBI
Punicalagin is an ellagitannin and a potent antioxidant in pomegranate juice. We showed that both...
- 4Punicalagin - Immunology & Inflammation - Selleck Chemicals
Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxida...
- 5Chemical structures of punicalagin and ellagic acid.
Punicalagin (PC) is an ellagitannin found in the fruit peel of Punica granatum. We have demonstra...