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中央研究院生物醫學科學研究所ACADEMIA SINICA INSTITUTE OF BIOMEDICAL SCIENCES · Home · Email · Faculty · 中文 ... Home AboutIBMS NewsandEvents Research Faculty AdministrativeStaff CoreFacilities EducationPrograms FundingOpportunity Jobs EpidemicPrevention ·AboutIBMS History CurrentDirector Executives DivisionsandAims AdministrativeOrganization ManpowerandTrainingPrograms ResearchAccomplishments AcademicAdvisoryCommittee SuccessiveAcademicAdvisoryCommittee SuccessivePreliminaryAdvisoryBoard(1981~1985) ·NewsandEvents News Seminars Conferences 研究領域開始--> ·Research Epidemiology&Genetics Neuroscience CardiovascularResearch InfectiousDisease&Immunology Cancer StructuralBiology 研究領域結束--> ·Faculty Epidemiology&Genetics Fann,CathyS.-J. Kwok,Pui-Yan Pan,Wen-Harn Shen,Chen-Yang Wu,Jer-Yuarn Lee,YunglingLeo Chen,Chien-Hsiun Li,Ling-Hui Chang,Yi-Cheng Ko,Tai-Ming Lin,Wen-chang Neuroscience Shyu,BaiChuang Chern,Yijuang Lee,EminyH.Y. Tang,TangK. Chen,Chien-Chang Chen,Chih-Cheng Huang,Yi-Shuian Lin,Teng-Nan Tarn,Woan-Yuh Hsu,Ching-Lung Lin,Wan-Chen Yang,Shi-Bing Cheng,Sin-Jhong Pan,Ming-Kai Wang,Guey-Shin CardiovascularResearch Hsieh,PatrickChing-Ho Yang,Ruey-Bing(Ray) Shyue,Song-Kun Yan,Yu-Ting Wang,Guey-Shin Lai,Shih-Lei(Ben) Chen,Yen-Hui Cheng,Ching-Feng Yang,Kai-Chien Hu,Yu-Feng Chen,Chien-Chang Hu,Che-Ming(Jack) InfectiousDisease&Immunology Lin,Yi-Ling Tao,Mi-Hua Yen,JeffreyJ.Y. Chang,Ya-Jen Hu,Che-Ming(Jack) Shui,Jr-Wen Tsai,Kevin Wang,I-Hsuan(Jessica) Chen,Huan-Yuan Shih,Hsiu-Ming Lee,YunglingLeo Cancer Roffler,SteveR. Jou,Yuh-Shan Lee,Te-Chang Lin,Wen-chang Shieh,Sheau-Yann Shih,Hsiu-Ming Chen,Shih-Yu Lee,Yu-Ru Li,Chia-Wei Wang,Shu-Ping Suzuki,Jun Li,Fu-An Yang,Pan-Chyr Tang,TangK. StructuralBiology Hwang,Ming-Jing Lim,Carmay Chen,Chinpan Hwang,DennisW. Mou,Yun Lin,Jung-Hsin ResearchScientist Chang,Yao-Ming Chen,Huan-Yuan Chen,Yen-Hui Chen,Chien-Hsiun Cheng,Sin-Jhong Li,Fu-An Li,Ling-Hui Visiting Hu, Yu-Feng Adjunct Chen,Jin-Jer Chen,JoanneJeou-Yuan Chen,SteveS.-L. Cheng,AndrewTaiAnn Ho,Mei-Shang Hung,ShihChieh Kannagi,Reiji Lee,MingTaMichael Shih,Chiaho Su,Tsann-Long Liao,You-Di Tai,Jung-Hsiang Emeritus Chai,Chok-Yung Chang,Chen Chen,Jin-Jer Chen,SteveS.-L. Chen,Yuan-Tsong Chen,JoanneJeou-Yuan Cheng,AndrewTaiAnn Ho,Mei-Shang Huang,Tai-huang Kannagi,Reiji Liu,Fu-Tong Su,Chun-Kuei Wang,DannyLing Wu,Cheng-Wen Yen,PaulineH. Chau,Lee-Young Liao,You-Di Liao,Fang Memorial Cheung,WaiYiu(1996) Yeung,HongN.(1997) Wu,FeliciaY.-H.(1999) Peck,Konan(2012) Lee,ShoTone(2016) Shieh,Ru-Chi(2017) ·AdministrativeStaff AdministrativeOffice OfficeofProcurement&PropertyManagement FloorSecretary GeneralAffairsOffice InformationTechnologyDepartment SafetyOffice MedicalArtDepartment ·CoreFacilities IBMS CommonEquipmentCore LightMicroscopy ChemicalSynthesis ProteomicsCore DNASequencing FlowCytometricAnalysis ExperimentalAnimalFacility PathologyCore BioIT AdenovirusLab ElectrophysiologyCore ComputationalMedicineCore AnimalImagingFacility AcademiaSinica InstrumentServiceDivision DNASequencing FlowCytometricSorting AffymetrixGeneExpressionServiceLab NeuroscienceProgramofAcademiaSinica(NPAS) HighFieldNuclearMagneticResonanceCenter P3Lab Adeno-AssociatedVirusCore InflammationCoreFacility(ICF) CardiacandStrokeAnimalModelCoreFacility ResourceCenterforTranslationalMedicine NationalCoreFacilityforBiopharmaceuticals(NCFB) NationalCenterforGenomeMedicine iPSCLab TaiwanAnimalconsortium TaiwanMouseClinic NationalBiotechnologyResearchPark(NBRP) TaiwanBiobank TaiwanMouseClinic ·EducationPrograms TaiwanInternationalGraduateProgram TIGPOn-lineApplicationSystem MolecularMedicine Bioinformatics ChemicalBiologyandMolecularBiophysics InterdisciplinaryNeuroscience NationalYangMingChiaoTungUniversityMolecularMedicineProgram GraduateInstituteofLifeSciencesNationalDefenseMedicalCenter ProgramofMicrobialGenomicsGraduateInstituteofMicrobiologyCollegeofMedicineNationalTaiwanUniversity DegreeProgram TranslationalMedicine SummerInternshipProgram ·FundingOpportunities |EpidemicPrevention|WebMail|Intranet|Publications|TaiwanBioBank|Links| ·CongratulationstoDirectorPui-YanKwokonbeingelectedasa2022FellowofTheWorldAcademyofSciences(TWAS). ·Congratulationsonwinningthe“2021IBMSResearchDay/TIGPTravelAwardCompetition”. ·PolyethyleneGlycolImmunogenicity:Theoretical,Clinical,andPracticalAspectsofAnti-PolyethyleneGlycolAntibodies ·Acriticalmoleculeforregulatinginflammatorycelldeaththroughintracellularbindingtomicrobialglycans LatestNews JobOpportunities Postdoc:14 ResearchAssociates:27 Others:1 MORE>> ▪ [News]Thelectureofthe2021MedicineNobelPrizewinner,Dr.ArdemPatapoutianatIBMSinDecember,2015...2021/10/19 ▪ [Research]Biomaterial-inducedconversionofquiescentcardiomyocytesintopacemakercells2021/12/08 ▪ [News]恭喜本所胡瑜峰客座副研究員榮獲國立成功大學第90週年「優秀青年校友」。

...2021/11/26 ▪ [Research]AnewstudyfromAcademiaSinicarevealswhysomepatientscleartheSARS-CoV-2virusfasterthanot...2021/11/15 ▪ [News]CongratulationstoDirectorPui-YanKwokonbeingelectedasa2022FellowofTheWorldAcademyofS...2021/11/02 ▪ [Research]UnravelingtheMysteriousRoleofCentriolarProteinCEP120inJoubertSyndrome,aCongenitalCerebe...2021/10/29 ▪ [News]Congratulationsonwinningthe“2021IBMSResearchDay/TIGPTravelAwardCompetition”.2021/10/26 MORE>> Seminars/Conferences Seminars Conferences ▪2021/12/27( Mon.)11:00-12:00CANCELEDAcommonvariantin11q23.3associatedwithhyperlipidemiaismediatedbythebindingandregulationofGATA4-APost-GWASstudy Dr.Shen,Chen-Yang沈志陽 MORE>> NoData-Conferences MORE>> ResearchHighlights Dr.Roffler,SteveR. Biomedicine&Pharmacotherapy,Dec06,2021 Impactofanti-PEGantibodyaffinityonacceleratedbloodclearanceofpegylatedepoetinbeta ......     Antibodiesthatbind polyethyleneglycol (PEG)canbeinducedbypegylatedbiomoleculesandalsoexistinasignificantfractionofhealthyindividualswhohaveneverreceivedpegylatedmedicines.The bind ......MORE Dr.Lee,YunglingLeo PediatricAllergyandImmunology,Dec02,2021 InvestigatingObesity-relatedRiskFactorsforChildhoodAsthma     Background: Wetestedthehypothesisthatmultipleobesity-relatedriskfactors(obesity,physicalactivity,cardiopulmonaryphysicalfitness,sleep-disorderbreathing(SDB),andsleepquality)areassociatedwithc ......MORE Dr.Li,Chia-Wei EBioMedicine,Nov25,2021 TargetingconservedN-glycosylationblocksSARS-CoV-2variantinfectioninvitro     Background: Despiteclinicalsuccesswithanti-spikevaccines,theeffectivenessofneutralizingantibodiesandvaccineshasbeencompromisedbyrapidlyspreadingSARS-CoV-2variants.Virusescanhijacktheglyc ......MORE Dr.Roffler,SteveR. Impactofanti-PEGantibodyaffinityonacceleratedbloodclearanceofpegylatedepoetinbetainmice Biomedicine&Pharmacotherapy,Dec06,2021 MORE Dr.Lee,YunglingLeo InvestigatingObesity-relatedRiskFactorsforChildhoodAsthma PediatricAllergyandImmunology,Dec02,2021 MORE Dr.Tarn,Woan-Yuh AntisenseOligonucleotide-BasedTherapyofViralInfections Pharmaceutics,Nov26,2021 MORE Dr.Li,Chia-Wei TargetingconservedN-glycosylationblocksSARS-CoV-2variantinfectioninvitro EBioMedicine,Nov25,2021 MORE Dr.Cheng,Ching-Feng TheATF3inducerprotectsagainstdiet-inducedobesityviasuppressingadipocyteadipogenesisandpromotinglipolysisandbrowning Biomedicine&Pharmacotherapy,Nov25,2021 MORE Dr.Hu,Yu-Feng Biomaterial-inducedconversionofquiescentcardiomyocytesintopacemakercellsinrats NatureBiomedicalEngineering,Nov22,2021 MORE Dr.Tarn,Woan-Yuh Dr.Yang,Ruey-Bing(Ray) TheY14-p53regulatorycircuitinmegakaryocytedifferentiationandthrombocytopenia iScience,Nov19,2021 MORE Dr.Chen,Chien-Chang FAKregulatescardiomyocytemitochondrialfissionandfunctionthroughDrp1 FEBSJournal,Nov05,2021 MORE Dr.Chen,Shih-Yu NKcellreceptorandligandcompositioninfluencestheclearanceofSARS-CoV-2 JournalofClinicalInvestigation,Nov01,2021 MORE Dr.Tang,TangK. CEP120-mediatedKIAA0753recruitmentontocentriolesisrequiredfortimelyneuronaldifferentiationandgerminalzoneexitinthedevelopingcerebell ...... Genes&Development,Oct28,2021 MORE Dr.Hsu,Ching-Lung Rapidsynapticplasticitycontributestoalearnedconjunctivecodeofpositionandchoice-relatedinformationinthehippocampus Neuron,Oct21,2021 MORE Dr.Li,Chia-Wei HyperglycosylatedspikeofSARS-CoV-2gammavariantinducesbreastcancermetastasis AmericanJournalofCancerResearch,Oct15,2021 MORE Dr.Hwang,DennisW. AGadoliniumDO3AAmidem-PhenylBoronicAcidMRIProbeforTargetedImagingofSialatedSolidTumors Biomedicines,Oct13,2021 MORE Dr.Chern,Yijuang Emergingrolesofdysregulatedadenosinehomeostasisinbraindisorderswithaspecificfocusonneurodegenerativediseases JournalofBiomedicalScience,Oct11,2021 MORE Dr.Chern,Yijuang Asystem-widemislocalizationofRNA-bindingproteinsinmotorneuronsisanewfeatureofALS NeurobiologyofDisease,Oct08,2021 MORE Dr.Chen,Chih-Cheng ASIC1aisrequiredforneuronalactivationvialow-intensityultrasoundstimulationinmousebrain eLife,Sep27,2021 MORE Dr.Tarn,Woan-Yuh DDX3modulatesthetumormicroenvironmentviaitsroleinendoplasmicreticulum-associatedtranslation iScience,Sep24,2021 MORE Dr.Roffler,SteveR. PolyethyleneGlycolImmunogenicity:Theoretical,Clinical,andPracticalAspectsofAnti-PolyethyleneGlycolAntibodies ACSNano,Sep02,2021 MORE Dr.Lee,Te-Chang Dr.Su,Tsann-Long DiscoveryofOralAnticancer1,2-Bis(hydroxymethyl)benzo[g]pyrrolo[2,1-a]phthalazineHybridsThatInhibitAngiogenesisandInduceDNACross-Links JournalofMedicinalChemistry,Aug30,2021 MORE Dr.Shen,Chen-Yang Bodymassindexandtype2diabetesandbreastcancersurvival:aMendelianrandomizationstudy AmericanJournalofCancerResearch,Aug30,2021 MORE MORE>> LINKS AS/IBMSCalendar Webmail Download(IBMSstaffsonly) Administrative&SupportingGroups LifeScienceLibrary Publications TaiwanBioBank AcrylicStudio Intranet(IBMSstaffsonly) AcademiaSinicaCounselingCenter(ASCC) EpidemicPrevention