Tundra Cryo TEM | Thermo Fisher Scientific - TW

The Tundra Cryo-TEM can visualize the impact of biochemical adjustments to samples faster than other technologies. Exchange samples in and out of the microscope ... PopularApplications&TechniquesShopAllProductsServicesSupport Signin QuickOrder     Search ThermoFisherScientific SearchAll Search Home›ElectronMicroscopy›ElectronMicroscopes›TransmissionElectronMicroscopes›TundraCryo-TEMTransmissionElectronMicroscopes TundraCryo-TEMAcryo-transmissionelectronmicroscopeacceleratingstructuralanalysison-site. ContactusKeyFeaturesSpecificationsResourcesSoftwareApplicationsTechniquesDocumentsContactUs4b51-Key/Specs/Resources/Software/Appl/Tech/Doc/ContactBringingcryo-electronmicroscopytoyouWhetheryou’reanexperiencedmicroscopist,orjuststartingout,theThermoScientificTundraCryo-TransmissionElectronMicroscope(Cryo-TEM)isadedicatedstructural-analysissolutiondesignedtobringcryo-electronmicroscopy(cryo-EM)toyourlaboratoryatanaffordablepricepoint.Simplifieddatacollectionandrapidsampleloading/unloadingmaketheTundraCryo-TEMapowerfultoolforansweringyourmostchallengingresearchquestions.WiththeTundraCryo-TEM,youcanobtainstructuresatbiologicallyrelevantresolutionsin-houseorreliablypreparehigh-qualitysamplesforfurtheranalysisonThermoScientificKriosorGlaciosCryo-TEMs. MolecularstructuresdeterminedusingtheTundraCryo-TEM  TundraCryo-TEMkeybenefitsCryo-TEMsamplepreparationandoptimizationTheTundraCryo-TEMcanvisualizetheimpactofbiochemicaladjustmentstosamplesfasterthanothertechnologies.Exchangesamplesinandoutofthemicroscopeinminutes,withnearlyinstantaneousfeedback,allowingyoutooptimizeyoursampleconditionsquicklywithoutextensivetraining.Cryo-EMstructuresatbiologicallyrelevantresolutionTheopticsoftheTundraCryo-TEMarespecificallydesignedsothatyoucananswerfundamentalquestionsonbiologyandhumandiseasewithdataatbiologicallyrelevantresolutions.Operatingat100kV,theTundraCryo-TEMcangeneratehigh-contrastbiologicalimagesdownto3.5Åatmediumthroughputwithitshigh-performance,fraction-enabledThermoScientificCetaCamera.MeetyourbudgetAwiderangeoffundingproposalsandgrantswereconsideredwhendesigningtheTundraCryo-TEMtokeepitspricewithinthereachofmostinstrumentationgrants.Our ElectronMicroscopyFundingSupportCenter hasadditionalinformationaboutourfinancialservicesaswellasgrant-writingguidancesoyoucangetthetoolsyouneed,whenyouneedthem.Artificialintelligencetakestheguessworkoutofcryo-TEMTheTundraCryo-TEMcomeswithacompletesuiteofautomationsoftwareforefficientoptimizationofyoursample’sbiochemistryaswellasdatacollectionforstructuraldetermination.Thisincludesauser-friendlyAI-enabledsoftwaresolutioncapableofanalyzingintermediateresults,providinginstantfeedback,andsteeringdatacollectiononthefly.OurAIalgorithmsarebasedonyearsofcryo-EMknowledge,providingexpertdecisionsupfronttoensurethatyourinstrumentisworkingatoptimalconditions.Focusonthescienceratherthanonfine-tuningthemicroscope. Cryo-TEMwebinarLearnmoreabouttheTundraCryo-TEMinthis30minuteon-demandwebinar,including:HowtomakeimpactfulstructuralbiologydiscoverieswiththeTundraCryo-TEM.Easiersampleloadingandretrievalwithournovel,semi-automatedloadingsystem.Andmore...Registertowatch  HowcantheTundraCryo-TEMhelpyou?Ifyou...Step1…Arenewtocryo-electronmicroscopyStep2…Alreadyownacryo-EMStep3…Usecryo-EMatasharedfacilityorCROStep4…Runacryo-EMcorefacilityorCROTheease-of-usefeaturesandguidedautomationoftheTundraCryo-TEMmakesiteasytogetstartedincryo-EMandoffersapricepointwithinthereachofmanygrantsandfundingsources.TheTundraCryo-TEMoffersefficientsampleiterationandoptimization.Trainnewteammembersoncryo-EMwithoutlosingvaluabletimeonyourGlaciosorKriosCryo-TEM.TheTundraCryo-TEMallowsyoutobringcryo-EMon-site;projectsthatdon’trequirehighestresolutionanalysisaren’tstuckwaitingoninstrumentswithhighdemand.Youcanalsoproducethebestpossiblesampleswhenoff-siteanalysisisneeded,sincetheTundraCryo-TEMallowsyoutoquicklyassessgridquality.Youcantrainnewteammembersoncryo-EMwithoutlosingvaluabletimeonyourGlaciosorKriosCryo-TEMs.TheTundraCryo-TEMalsoactsasadedicatedmicroscopeforquicksamplequalityassessment. Step1: …Arenewtocryo-electronmicroscopyTheease-of-usefeaturesandguidedautomationoftheTundraCryo-TEMmakesiteasytogetstartedincryo-EMandoffersapricepointwithinthereachofmanygrantsandfundingsources. Step2: …Alreadyownacryo-EMTheTundraCryo-TEMoffersefficientsampleiterationandoptimization.Trainnewteammembersoncryo-EMwithoutlosingvaluabletimeonyourGlaciosorKriosCryo-TEM. Step3: …Usecryo-EMatasharedfacilityorCROTheTundraCryo-TEMallowsyoutobringcryo-EMon-site;projectsthatdon’trequirehighestresolutionanalysisaren’tstuckwaitingoninstrumentswithhighdemand.Youcanalsoproducethebestpossiblesampleswhenoff-siteanalysisisneeded,sincetheTundraCryo-TEMallowsyoutoquicklyassessgridquality. Step4: …Runacryo-EMcorefacilityorCROYoucantrainnewteammembersoncryo-EMwithoutlosingvaluabletimeonyourGlaciosorKriosCryo-TEMs.TheTundraCryo-TEMalsoactsasadedicatedmicroscopeforquicksamplequalityassessment.  TundraCryo-TEMsupportStyleSheetforInstrumentCardsOriginalCryo-EMFundingCenterSecuringfundingcanbedemanding,time-consuming,andstressful.OurCryo-EMFundingCenteroffersproposalwritingtoolsaswellasaccesstotechnicalexpertswhocanguideyouthroughtheprocess.ViewsupportcenterTundraCryo-EMserviceandsupportOurserviceandsupportoptionsensurethatyoumaximizeyourinstrumentuptimeanddataquality.  DownloadbrochureCryo-EMAsktheExpertsSeriesWatchandengagewithcryo-electronmicroscopyresearcherswhiletheydiscussthepracticalandtheoreticalaspectsoftheirwork.Registernow  TundraCryo-TEMspecificationsTechnicalhighlightsoftheTundraCryo-TEM3.5Åapoferritinstructuredeterminationin24-72hoursHigh-brightnessX-FEG(extremefieldemissiongun)Fixedacceleratingvoltageof100kVSemi-automatedsampleloadingCryo-preparationstationallowingcontamination-freesampleexchangeSampletransferdevicefortransferringsingleAutoGridstothemicroscope Fixedcryo-boxthatkeepssamplescontaminationfreeforupto72hoursComputerizedspecimencryo-stageHigh-performanceThermoScientificCetaCamerawithdosefractionation,optimizedforlow-doseimagingSmartEPUSoftwareforautomatedsingleparticleanalysisscreeninganddataacquisition.Includesanopenapplicationprogramminginterface  TundraCryo-TEMresources VideosWebinarTheTundraCryo-TEMisadedicatedstructure-determinationsolutiondesignedtobringsingleparticleanalysistoeverybiochemistrylaboratory.Dr.JiriNovacekfromCEITEC,MasarykUniversity,discusseshowcryo-EMisacceleratinghisplantresearch,byunderstandingthestructureandfunctionofplumpoxvirus.Dr.JaredAuclair,DirectorofBiopharmaceuticalAnalysisLaboratory,NorthwesternUniversity,talksaboutusingtheTundraCryo-TEMtogatherdataonmoleculesincludingbatch-to-batchconsistency.Theautomation,flexibility,andintegrationofcryo-EMiscriticalinbiopharmaceuticallaboratories.Dr.JamesWhisstock,professorfromMonashUniversity,discusseshowtheTundraCryo-TEMcancollectcompletedatasetsatnearatomicresolutioninlessthanafewdaysforstructuraldrugdiscovery.Cryo-TEMwebinarLearnmoreabouttheTundraCryo-TEMinthis30minuteon-demandwebinar,including:HowtomakeimpactfulstructuralbiologydiscoverieswiththeTundraCryo-TEM.Easiersampleloadingandretrievalwithournovel,semi-automatedloadingsystem.Andmore...Registertowatch Videos TheTundraCryo-TEMisadedicatedstructure-determinationsolutiondesignedtobringsingleparticleanalysistoeverybiochemistrylaboratory.Dr.JiriNovacekfromCEITEC,MasarykUniversity,discusseshowcryo-EMisacceleratinghisplantresearch,byunderstandingthestructureandfunctionofplumpoxvirus.Dr.JaredAuclair,DirectorofBiopharmaceuticalAnalysisLaboratory,NorthwesternUniversity,talksaboutusingtheTundraCryo-TEMtogatherdataonmoleculesincludingbatch-to-batchconsistency.Theautomation,flexibility,andintegrationofcryo-EMiscriticalinbiopharmaceuticallaboratories.Dr.JamesWhisstock,professorfromMonashUniversity,discusseshowtheTundraCryo-TEMcancollectcompletedatasetsatnearatomicresolutioninlessthanafewdaysforstructuraldrugdiscovery. Webinar Cryo-TEMwebinarLearnmoreabouttheTundraCryo-TEMinthis30minuteon-demandwebinar,including:HowtomakeimpactfulstructuralbiologydiscoverieswiththeTundraCryo-TEM.Easiersampleloadingandretrievalwithournovel,semi-automatedloadingsystem.Andmore...Registertowatch  SmartEPUsoftwareforCryo-TEMUser-friendlysoftwareforday-to-dayoperationMicroscope-embeddedsolutionforsingleparticleanalysisanddataacquisitionReducedneedforpriorexpertise:softwareassistswithexperimentalset-up,providingreal-timefeedbackOptimizedforhigh-throughputparticlecollectionTheopenAPIofSmartEPUSoftwareallowsyoutodevelopyourownfunctionsfortheTundraCryo-TEM.MaximizedeaseofuseandefficiencyTheembeddedtraffic-lightUIelementindicatesthemicroscope’sstatus.Predefinedtemplatesfortypicalusecasesallowyoutobegincollectinghigh-resolutiondatawithonlyafewclicks.AI-enabledsoftwareSmartEPUSoftware’sautomationandAI-drivenpluginsguidetheuserthroughcriticaldecisionpointsand,insomecases,makedecisionsautomatically,reducingtheneedformanualuserintervention.  TundraCryo-TEMapplicationsStyleSheettoremoveellipsisonKomodoTabsstylesheetInfectiousDiseaseResearchCryo-EMtechniquesenablemultiscaleobservationsof3Dbiologicalstructuresintheirnear-nativestates,informingfaster,moreefficientdevelopmentoftherapeutics.StructuralBiologyResearchCryo-electronmicroscopyenablesthestructuralanalysisofchallengingbiologicaltargetssuchaslargecomplexes,flexiblespeciesandmembraneprotein.NeurodegenerativeDiseaseResearchCryo-EMcandeterminethestructuralfeaturesofproteinaggregatesimplicatedinneurodegenerativediseases,allowingscientiststoaddresshowtheyform,interactwiththecellularenvironment,andalterbrainfunction.  TundraCryo-TEMtechniquesSingleParticleAnalysisSingleParticleAnalysisSingleparticleanalysis(SPA)isacryo-electronmicroscopytechniquethatenablesstructuralcharacterizationatnear-atomicresolutions,unravelingdynamicbiologicalprocessesandthestructureofbiomolecularcomplexes/assemblies.Learnmore › SingleParticleAnalysis SingleParticleAnalysisSingleparticleanalysis(SPA)isacryo-electronmicroscopytechniquethatenablesstructuralcharacterizationatnear-atomicresolutions,unravelingdynamicbiologicalprocessesandthestructureofbiomolecularcomplexes/assemblies.Learnmore › TundraCryo-TEMdocumentsBrochure:TundraCryo-TEMBrochure:ServicePortfolioforTundraCryo-TEMDatasheet:TundraCryo-TEMeBook:Getstartedwithcryo-electronmicroscopyeBook:TundraCryo-TEMfordrugdiscoveryDatasheet:Instrumentationandresourcesforthepreparationofcryo-EMsamplesDatasheet:Guidanceforplanningacryo-TEMlaboratoryContactusStyleSheetforKomodoTabsStyleSheettochangeH2styletopwithem-h2-headerclassStyleSheettochangeSampleH3topwithem-h3-headerclassStyleSheettochangeH3topwithem-h3-headerclassStyleSheettochangeApplicationsH3topwithem-h3-headerclassStyleSheetforProductsTableSpecificationsElectronmicroscopyservicesToensureoptimalsystemperformance,weprovideyouaccesstoaworld-classnetworkoffieldserviceexperts,technicalsupport,andcertifiedspareparts.Learnmore›ElectronmicroscopysupportandresourcesAcceleratingMicroscopyblog›Softwareupdates›Servicerequest›Servicecontracts›Partsinquiry›StyleSheetforSupportandServicefooterStyleSheetforFontsStyleSheetforCards Signin Don'thaveanaccount? 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